Use PICO as tool to analyze the parts of your question
P | I | C | O |
People/ Patient/ Problem | Intervention/ Exposure | Comparison | Outcomes |
What are the important characteristics of the patients &/or problem? | What you plan to do for the patient or problem? | What, if anything, is the alternative to the intervention? | What is the outcome that you would like to measure? |
People who exercise | warm up before exercise | no warm up | injury prevention |
PICO is a good framework to help clarify your systematic review question.
Beyond PICO: the SPIDER tool for qualitative evidence synthesis.
1. Gather together your team.
2. Develop your protocol.
3. Data collection, locate, screen and collect studies
4. Abstract data and appraise risk of bias in the individual studies.
5. Synthesize findings, interpret and assess overall body of evidence.
6. Write report
7. Update
Centre for Evidence-Based Medicine
The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare.
Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.
Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.
Evidence-Based health care
Evidence-Based medicine
Evidence-Based public health
Evidence-Based policy
Source: “EBM Pyramid.” Digital Image. Eli M. Oboler Library, 27 May 2016.
1. Frame your research question (PICO/ PECO)
2. Develop search strategy.
3. Develop protocol
4. Run search strategy in at least two databases.
5. Retrieve and de-duplicate citations
6. Develop system for screening titles/ abstracts and full text.
7. Screen titles or/ abstracts
8. Retrieve and screen full text.
Online Books Freely available
1. Finding what works in Health Care: standards for systematic reviews by Institute of Medicine
2. Cochrane Handbook for Systematic Reviews of Interventions by Julian Higgins and Sally Green
University of the Western Cape,
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