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A Primer of Population Genetics and Genomics by
A Primer of Population Genetics and Genomics has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.Recent textbooks have tended to focus on such specialized topics as the coalescent, molecular evolution, human population genetics, or genomics. This primer bucks that trend by encouraging a broader familiarity with, and understanding of, population genetics and genomics as a whole. The overviewranges from mating systems through the causes of evolution, molecular population genetics, and the genomics of complex traits. Interwoven are discussions of ancient DNA, gene drive, landscape genetics, identifying risk factors for complex diseases, the genomics of adaptation and speciation, andother active areas of current research. The principles are illuminated by numerous examples from a wide variety of animals, plants, microbes, and human populations. The approach also emphasizes learning by doing, which in this case means solving numerical or conceptual problems. The rationale behindthis is that the use of concepts in problem-solving lead to deeper understanding and longer knowledge retention.This accessible, introductory textbook is aimed principally at students of various levels and abilities (from senior undergraduate to postgraduate) as well as practising scientists in the fields of population genetics, ecology, evolutionary biology, computational biology, bioinformatics,biostatistics, physics, and mathematics.
Bioinformatics with Python Cookbook by
Discover modern, next-generation sequencing libraries from Python ecosystem to analyze large amounts of biological data Key Features Perform complex bioinformatics analysis using the most important Python libraries and applications Implement next-generation sequencing, metagenomics, automating analysis, population genetics, and more Explore various statistical and machine learning techniques for bioinformatics data analysis Book Description Bioinformatics is an active research field that uses a range of simple-to-advanced computations to extract valuable information from biological data. This book covers next-generation sequencing, genomics, metagenomics, population genetics, phylogenetics, and proteomics. You'll learn modern programming techniques to analyze large amounts of biological data. With the help of real-world examples, you'll convert, analyze, and visualize datasets using various Python tools and libraries. This book will help you get a better understanding of working with a Galaxy server, which is the most widely used bioinformatics web-based pipeline system. This updated edition also includes advanced next-generation sequencing filtering techniques. You'll also explore topics such as SNP discovery using statistical approaches under high-performance computing frameworks such as Dask and Spark. By the end of this book, you'll be able to use and implement modern programming techniques and frameworks to deal with the ever-increasing deluge of bioinformatics data. What you will learn Learn how to process large next-generation sequencing (NGS) datasets Work with genomic dataset using the FASTQ, BAM, and VCF formats Learn to perform sequence comparison and phylogenetic reconstruction Perform complex analysis with protemics data Use Python to interact with Galaxy servers Use High-performance computing techniques with Dask and Spark Visualize protein dataset interactions using Cytoscape Use PCA and Decision Trees, two machine learning techniques, with biological datasets Who this book is for This book is for Data data Scientistsscientists, Bioinformatics bioinformatics analysts, researchers, and Python developers who want to address intermediate-to-advanced biological and bioinformatics problems using a recipe-based approach. Working knowledge of the Python programming language is expected.
Envisioning the Framework by
Data visualization--making sense of the world through images that tell a story--has a history that parallels human existence. The strength of visualization lies in its ability to reveal truth out of information that may remain hidden in lines of text, large data sets, or complex ideas. The Framework for Information Literacy for Higher Education presents complex threshold concepts, developed intentionally without prescriptive lists of skills and with flexible options for implementation, which can be explored and understood through visualization. Envisioning the Framework offers a visual opportunity for thought, discovery, and sense-making of the Framework and its concepts. Seventeen chapters packed with full-color illustrations and tables explore topics including: LibGuides creation through conceptual integration with the Framework fostering interdisciplinary transference the convergence of metaliteracy with the Framework teaching multimodalities and data visualization mapping a culturally responsive information literacy journal for international students Chapters include content for credit-bearing information courses, one-shots, and teaching first-year students. Twenty-first-century information literacy involves the metaliterate learner, reflects seismic changes in the duties and roles of teaching librarians, requires new partnerships with faculty and instructional designers, and emphasizes continuous assessment practices. Envisioning the Framework can help you use symbols and visuals for deeper understanding of the Framework, to map the Framework with teaching and learning objectives, and to tell a coherent story to students featuring the frames and the Framework.
Contemporary Management Principles 2e by
Change is the distinguishing characteristic of the business environment across the world and it affects how contemporary organisations operate. While organisations need to do more with less, they also have to satisfy the needs of their customers who, with more exposure to local and global markets, have higher expectations relating to the cost, quality, speed and innovation of the services and products they purchase from these organisations. In response to the changes in their business environment, organisations are becoming flatter, networked, global, more flexible and diverse and managers have to acquire the skills to face the challenges associated with these features.
The Struggle for Health by
The first edition of The Struggle for Health was published in 1985 and was widely acclaimed by those seeking a broader and deeper political understanding of ill health, beyond the medical model of care. It was a revolutionary book, charting new ways of understanding and tackling the causes of ill health, and suggesting strategies to enable health for all. This second edition includes health problems that have emerged since the 1980s, notably HIV/AIDs, COVID-19, and other epidemics, and the increase in non-communicable diseases, such as cardiovascular disease and diabetes. It examines some of the health impacts of globalization, specifically on the food and pharmaceutical value chains, and considers the consequences of climate change on the health of populations. However, this edition does not depart from the core message of the original book: Health for All can only be achieved through a more equitable distribution of wealth, resources, and power. The Struggle for Health, Second Edition, utilises the same approach as the first, with a narrative that begins with diseases, then describes historical trends and the limitation of the medical (and commercial) model of care. At each juncture, it asks the question 'WHY' - why do people, especially children, still die in large numbers throughout the world, from wholly preventable diseases? Why is it that appropriate provision for health care is not available to every individual in the world? What changes can be made to improve this situation? Most importantly, this edition presents a strengthened call to action, building upon the original work and advocating for systemic changes to ensure justice and equity in health for all.
Universities on fire : higher education in the climate crisis / by
Scientists agree that we are on the precipice of a global climate crisis. How will it transform colleges and universities? In 2019, intense fires in the San Francisco Bay Area closed universities and drove afflicted people to shelter at other campuses. At the same time, extraordinary fires ravaged eastern Australia. Several universities responded by promising material and research support to damaged businesses while also hosting refugees and emergency response teams in student residence halls. This was an echo of the devastation wreaked by Hurricane Katrina on Tulane University in 2005. InUniversities on Fire, futurist Bryan Alexander explores higher education during an age of unfolding climate crisis. Powered by real-world examples and the latest research, Alexander assesses practical responses and strategies by surveying contemporary programs and academic climate research from around the world. He establishes a model of how academic institutions may respond and offers practical pathways forward for higher education. How will the two main purposes of education--teaching and research--change as the world heats up? Alexander positions colleges and universities in the broader social world, from town-gown relationships to connections between how campuses and civilization as a whole respond to this epochal threat. Current studies of climate change trace the likely implications across a range of domains, from agriculture to policy, urban design, technology, culture, and human psychology. However, few books have predicted or studied the effects of the climate crisis on colleges and universities. By connecting climate research to a deep, futures-informed analysis of academia, Universities on Fire explores how climate change will fundamentally reshape higher education.
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